GENETICS AND PERIODONTAL DISEASE

Although a high risk for progression of periodontitis is associated with the bacterial biofilm found in the gingival pocket, genetic variability of the host may influence an individual’s risk for disease development and the rate of periodontitis progression. Polymorphisms in cell signaling messengers IL-1A, IL-1B, IL-6, IL-10, MMP-3 (chronic form), and MMP-9 (chronic form) were […]

TRIPHALA EXTRACT COMPARED TO CHLORHEXIDINE (Peridex) mouthwash against plaque and gingival inflammation

METHODS: A double blinded parallel arm randomised control trial with 60 participants aged 18‐ 24 years. Participants were randomly allotted to 0.6% triphala, 0.12% chlorhexidine or colored saline mouthwash and examined after 21 days. During the experimental period, participants rinsed with the allocated mouth rinse 10ml twice daily for 30 seconds. The plaque and gingival […]

HORMONES and periodontal disease

The action of hormones changes the effectiveness of the epithelial barrier to bacterial insult and collagen maintenance and repair. An exaggerated inflammatory response of periodontal tissues may be seen during puberty, pregnancy and at the postmenopausal stage with the variation in the level of sex steroid hormone at different lifetimes.