“Antibiotics are commonly prescribed for aggressive periodontitis some cases of severe chronic periodontitis as an adjunct to periodontal debridement. However, the emergence of bacterial resistance is increasingly limiting their effectiveness and has directed researchers to test the antimicrobial efficacy of several natural products, such as essential oils and bee products. Numerous studies have shown that […]

Curcuma longa is an extract from the root of turmeric, a commonly used spice. It has also been used as a healing agent in Ayurvedic medicine for thousands of years. Recently, its anti-inflammatory, antibacterial, antifungal properties and antioxidant effects have been studied extensively. A study by P. L. Ravishankar compared curcumin gel to a prescription […]

“A diet low in carbohydrates, rich in Omega-3 fatty acids, rich in vitamins C and D, and rich in fibers can significantly reduce gingival and periodontal inflammation.”

“ An analysis of the literature shows that vitamin D plays a significant role in maintaining healthy periodontal and jaw bone tissues, alleviating inflammation processes, stimulating post-operative healing of periodontal tissues and the recovery of clinical parameters. Hiremath et al. conducted a random sampling of clinical research to prove the anti-inflammatory effect of vitamin D […]

“… bacterial communities lodged below the gumline may breach the normal barrier between the oral cavity and circulation, thus exposing bacterial components to the immune system and provoking antibody responses. These antibodies may then cross-react with self proteins to generate or exacerbate autoimmune conditions.”

“A growing body of evidence is accumulating supporting the direct and indirect impact of periodontal pathogens on systemic health. Epidemiological, clinical, and experimental studies have revealed the often overlooked relationship between bacteremia or inflammation due to periodontal disease and systemic disease.”

“When periodontitis occurs, reactive oxygen species, which are overproduced mostly by hyperactive neutrophils, could not be balanced by antioxidant defense system and cause tissues damage. This is characterized by increased metabolites of lipid peroxidation, DNA damage and protein damage”

“Inflammaging, defined as an age-related increase in the levels of pro-inflammatory markers in blood and tissues, is a strong risk factor for multiple diseases that are highly prevalent and frequent causes of disability in elderly individuals but are pathophysiologically uncorrelated.” https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6146930/

“Known since antiquity, periodontitis became prevalent after the domestication of plants and animals in Neolithic societies (≈10,000 years ago) when the oral microbiota underwent a distinct compositional shift — with increased frequency of Porphyromonas gingivalis and other periodontitis-associated species — compared with earlier hunter-gatherer societies. In its severe form, which afflicts 8.5% of U.S. adults, […]

“Periodontal tissues require adequate levels of antioxidants to prevent tissue damage caused by reactive oxygen species….Antioxidants are compounds that prevent the initiation or progression of oxidation reactions by trapping oxygen in the environment. They play an important role in preserving the structural integrity of cells and tissues, by maintaining their normal functions and ensuring the […]